About BioBricks
Synthesis and sequencing services compared on the prices vendors actually publish, verified and dated
What is on this site
6 guides, each with its sources on the page , 12 answers to the questions around them , and the comparison.
- Gene synthesis pricing: Gene synthesis is quoted per base pair, and the per-base headline is the number vendors compete on hardest: it is printed on the front of the service page, it moves with promotional cycles, and it is almost never what you finally pay.
- Custom oligo synthesis: Custom oligos are the highest-volume line most labs buy, and the pricing is deceptively layered: a per-base rate, a synthesis scale, a purification grade and any modification are four separate multipliers on the same order.
- Plasmid DNA preparation: Outsourced plasmid prep is bought for two quite different reasons: to save bench time on routine constructs, and to get a grade of DNA a normal lab cannot reliably produce.
- Custom synthesis services: "Custom synthesis" covers a wide span of work: nucleic acids, peptides, small molecules and proteins, all made to a customer specification rather than sold from a catalogue.
- RNA sequencing services: An RNA sequencing quote is built from three things that are often bundled into one number: library preparation, sequencing depth, and the analysis you get back.
- Custom siRNA synthesis: Custom siRNA sits between routine oligo synthesis and specialist nucleic acid manufacture.
Where the figures come from
Synthesis and sequencing service prices verified against each vendor's own published pages on 2026-08-24 by hubs/biobricks.org/ingest_vendors.py: every quoted figure re-fetched and matched verbatim (hash-pinned); class coverage evidenced by the vendor's live service page.
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