Science lab equipment for a new laboratory: what to buy, what to share, and what to leave until the science lab equipment budget is proven
Equipping a laboratory from nothing rewards restraint. The instruments that get used every day are unglamorous and cheap; the ones that look impressive in a start-up plan are frequently used monthly and would have been better accessed elsewhere for the first year. This page sets out a core list that almost every wet laboratory needs, the equipment usually better shared, and how to decide between the two.
- the OSHA laboratory standard requiring a written chemical hygiene plan
- 1910.1450
- hazard communication, which decides what a container must tell the user
- 1910.1200
- the CDC and NIH handbook that sets biosafety levels and containment practice
- BMBL
Figures in this panel are the standards this class of equipment is specified and inspected against, named from the regulations themselves and linked in the sources below. They are identifiers, not prices: BioBricks publishes verified prices for synthesis services only, and does not claim an equipment price index it has not measured.
- 4 vendor service pages verifiedevery figure matched verbatim to the vendor's page
- Quoted and dated, never estimatedlast verification pass 2026-08-24
- 1 service classes coveredeach with measured search demand behind it
Building the list
- Start with what is used daily. Pipettes and tips, a balance, a pH meter, a centrifuge, a vortex, water baths or heat blocks, a fridge and freezer, and adequate storage. These cost a fraction of one large instrument and they determine whether the laboratory can work at all.
- Then the containment your work requires. A fume hood for chemistry, a biosafety cabinet for biological work at the relevant containment level, and the emergency equipment that goes with either. What you handle decides which, and this is a compliance question rather than a preference.
- Cold storage is bought twice. Laboratories consistently underestimate freezer capacity and then buy an emergency second unit at a bad moment. Size generously, plan the power and heat load, and put an alarm and a documented failure plan on anything holding irreplaceable material.
- Share the large instruments at first. Sequencers, mass spectrometers, imaging systems and flow cytometers are usually available through core facilities or external providers. Using them that way for a year tells you what you actually need before the capital is committed.
- Buy service and consumables into the plan. Every instrument carries recurring cost, and a fit-out plan that lists only capital will be short within months. Put calibration, service and consumables into the operating budget from the start.
New against refurbished
Robust mechanical equipment such as centrifuges, incubators, water baths and shakers is often excellent value refurbished from a specialist who warrants the work. Anything with embedded software and a support lifetime deserves more caution, because software support ends before mechanical life does.
Ask the same questions either way: what was replaced, what warranty applies, whether the manufacturer will support it, and whether licences transfer.
The duties that arrive with the equipment
A working laboratory owes a chemical hygiene plan, training records, hazard labelling, maintenance and calibration schedules and a documented waste route. None of that is expensive at the start and all of it is painful to reconstruct later.
Keep an asset register from the first purchase: what it is, where it is, when it was serviced and calibrated, and who is trained on it. It takes minutes per instrument and answers most of what an inspector will ask.
Common questions
- What equipment does a new laboratory need first?
- The everyday items: pipettes and tips, a balance, a pH meter, a centrifuge, a vortex, heating and cooling, a fridge and freezer, and storage, plus whatever containment the work requires. These decide whether the laboratory can function.
- Should a new lab buy large instruments?
- Usually not in the first year. Core facilities and external providers give access to sequencers, mass spectrometers and imaging systems, and a year of that tells you what the real requirement is before capital is committed.
- How much freezer capacity do we need?
- More than the initial estimate, with alarms and a documented failure plan for anything irreplaceable. Under-sizing cold storage is the most reliably repeated mistake in laboratory fit-outs.
- Is refurbished equipment suitable for a new lab?
- For robust mechanical equipment from a specialist who warrants it, yes, and it stretches a first budget considerably. Be more cautious with instruments whose value depends on software that may lose support.
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Sources
Cite or embed this figure
The median advertised gene synthesis price per base pair in the US research synthesis services market was $0.11 in August 2026, across 4 verified vendor service pages recorded in BioBricks Synthesis Price Index.
Cite as: "BioBricks Synthesis Price Index", updated 2026-08-24, https://biobricks.org/science-lab-equipment/.