Custom oligos: vendors compared on published prices

Vendors with an evidenced Custom oligos service

A vendor appears here when its own live service page for Custom oligos answered at the linked URL on the date shown. Prices in the table are each vendor's advertised entry prices; sequence complexity, length, turnaround and delivery format change the quoted total.

Choosing an oligo supplier

Price the whole range, not the routine line. Plain desalted primers and dual-labelled probes are bought from the same supplier most weeks and are priced by completely different levers, so a supplier chosen on the primer rate alone will often be the wrong one for the probe spend.

Match scale to use. The smallest scale offered covers routine PCR comfortably, and over-ordering scale is the most common oligo overspend; primers are cheap to re-order and do not improve with storage.

Shipping and despatch commitments are part of the cost for a lab that orders weekly, and they can outweigh a per-base difference entirely.

Common questions

What do custom oligos cost?

Per base at the vendor's standard scale with desalting, plus uplifts for purification and each modification. The priced vendors below are quoted from their own pages; modified and HPLC-purified oligos cost substantially more than the entry rate.

Which oligo supplier should I use?

The one whose catalogue covers your modifications and whose despatch time fits how you work, at a rate you have checked. For most labs the modification range and turnaround matter more than the per-base rate.

Do these prices include purification?

Desalting is standard and is what an entry rate assumes. HPLC and PAGE purification are separate uplifts at every supplier, and the source page linked beside each figure states what the quoted rate covers.